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4.6 Hazards and Hazardous Materials
4.6HAZARDS AND HAZARDOUS MATERIALS
This section describes the potential adverse impacts on human health and the environment due to
exposure to hazardous materials or conditions that could be encountered as a result of implementation
of the proposed project. Hazardous materials include, but are not necessarily limited to, inorganic and
organic chemicals, chemical reagents and reaction products, solvents, mercury, lead, asbestos,
radioisotopes, fuels, oils, paints, cleansers, pesticides, and biohazardous substances that are used in
activities such as laboratory research, biotechnology manufacturing, and building and grounds
maintenance. Hazardous materials use at biotechnology centers generate hazardous by-products that
must eventually be handled and disposed of as hazardous wastes.
For the purposes of this analysis, hazardous materials include inorganic and organic chemicals and
products containing such substances as defined by California laws and regulations, radioactive materials,
and biohazardous materials. Potential effects include those associated with contaminated sites and the
potential exposure to hazardous materials used, stored, transported, or disposed of during construction
activities (such as exposure to asbestos or lead as a result of building demolition) or Genentech
operations. Potential impacts to water quality from construction-related surface water runoff that could
contain hazardous materials and/or from groundwater dewatering during construction or operation of
the proposed project are discussed in Section 4.2 (Flood and Inundation Hazards) of the MEIR. Impacts
related to toxic air contaminants that could be emitted during operation of the project are discussed in
Section 4.3 (Air Quality) of the MEIR. Seismic activity that poses a potential hazard to the project site is
discussed in Section 4.5 (Geology and Soils) of the MEIR.
Data used to prepare this section was taken from various sources, including information provided by
Genentech, the Genentech website, San Mateo County Environmental Health Department?
Environmental Health Division (SMCEHD) records (including hazardous materials inventory), and the
following reports prepared by Environmental Data Resources, Inc. in March 2006: (1) City Directories
dating back to 1990, (2) Aerial Photographs dating back to 1946, (3) Historical Topographic Maps dating
back to 1913, and (4) a report of hazardous materials sites located within a half-mile of the ?center? of
the Genentech Campus (approximately ?1000 Grandview Drive?), also referred to as MEIR Study Area.
Full bibliographic entries for all reference materials are provided in Section 4.6.4 (References) of this
chapter.
No comment letters related to hazardous materials or wastes were received in response to the
December 9, 2005, Revised Notice of Preparation (NOP) circulated for the project. In addition, no
comments were received at the public scoping meeting held January 17, 2006. The NOP and comment
letters are included in Appendix A of the MEIR.
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4.6.1Existing Conditions
Definitions
Hazard
A hazard is any situation that has the potential to cause damage to human health and the environment.
The risk to human health and the ecological environment is determined by the probability of exposure to
hazardous material and severity of harm such exposure would pose. That is to say, the likelihood and
means of exposure, in addition to the inherent toxicity of a material, are used to determine the degree of
risk to human health or the ecosystem. For example, a high probability of exposure to a low toxicity
chemical would not necessarily pose an unacceptable human health or ecological risk, whereas a low
probability of exposure to a very high toxicity chemical might. Various regulatory agencies, such as the
U.S. Environmental Protection Agency (EPA), State Water Resources Control Board and the Regional
Boards, the California Department of Toxic Substances Control (DTSC), and state and federal
Occupational Safety and Health Administrations (OSHA) are responsible for developing and/or
enforcing risk-based standards to protect the public and the environment.
Hazardous Material
The term ?hazardous material? is defined in different ways for different regulatory programs. This MEIR
uses the following definition of a hazardous material, provided in Sections 25501 (o) of the California
Health and Safety Code:
Any material that, because of its quantity, concentration, or physical or chemical characteristics,
poses a significant present or potential hazard to human health and safety or to the environment if
released into the workplace or the environment. ?Hazardous Materials? include, but are not limited
to, hazardous substances, hazardous wastes, and any material which a handler or the administering
agency has a reasonable basis for believing that it would be injurious to the health and safety of
persons or harmful to the environment if released into the workplace or environment.
By convention, most hazardous materials are thought to be hazardous chemicals, but certain radioactive
and biohazardous materials, as defined here, are also hazardous. A ?hazardous waste,? for the purposes
of this analysis, is any hazardous material that is abandoned, discarded, or recycled, as defined by
Section 25124 of the California Health and Safety Code. In addition, hazardous wastes occasionally may
be generated by actions that change the composition of previously nonhazardous materials. The criteria
that characterize a material as hazardous include ignitability, toxicity, corrosivity, reactivity, radioactivity,
or bioactivity.
Hazard vs. Risk
Workers and general public health are potentially at risk whenever hazardous materials have been used or
where an exposure to such materials could occur as a result of the presence of unidentified fill materials
or historic uses of a site. Inherent in the setting and analyses presented in this section are the concepts of
the ?hazard? of these materials and the ?risk? they pose to human health and the ecological
environment. Exposure to some chemical substances may harm internal organs or systems in the human
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body, ranging from temporary effects to permanent disability, or death. Hazardous materials that result
in adverse effects are generally considered ?toxic.? Other chemical materials, however, may be corrosive,
or react with other substances to form other hazardous materials, but they are not considered toxic
because organs or systems are not affected. Because toxic materials can result in adverse health effects,
they are considered hazardous materials, but not all hazardous materials are necessarily ?toxic.? For
purposes of the information and analyses presented in this section, the terms hazardous substances or
hazardous materials are used interchangeably and include materials that are considered toxic.
Acute vs. Chronic Health Effect
Whether a person exposed to a hazardous substance would suffer adverse health effects depends upon a
complex interaction of factors to determine the effects of exposure to hazardous materials: the exposure
pathway (the route by which a hazardous material enters the body); the amount of material to which the
person is exposed; the physical form (e.g., liquid, vapor) and characteristics (e.g., toxicity) of the material;
the frequency and duration of exposure; and the individual's unique biological characteristics, such as age,
gender, weight, and general health. Adverse health effects from exposure to hazardous materials may be
short-term (acute) or long-term (chronic). Acute effects can include damage to organs or systems in the
body and possibly death. Chronic effects, which may result from long-term exposure to a hazardous
material, can also include organ or systemic damage, but chronic effects of particular concern include
birth defects, genetic damage, and cancer. In the case of pathogenic (disease-causing) organisms or
biohazardous materials, for transmission to humans to occur, the pathogen must be present in
sufficiently high numbers to cause infection, and contact with the organism must occur.
Historical Use
Topographic Maps
Historical topographic maps dating back to 1913 were reviewed to assist in determining if past uses
within the MEIR Study Area involved hazardous materials. Table 4.6-1 provides a summary of these past
uses.
Aerial Photographs
Historical aerial photographs dating back to 1946 were reviewed to determine past uses at the proposed
project site. Table 4.6-2 provides a summary of these past uses.
Genentech Policy, Practice, & Performance
Genentech engages in the research, development, manufacture, and marketing of biotechnology products
for serious or life-threatening diseases, including commercialization of those products. Research at
Genentech focuses primarily on three areas of medicine: oncology, immunology and tissue growth and
repair.
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Table 4.6-1 Historical Topographic Map Information
1913 The proposed project site is primarily vacant undeveloped land. Several small structures are depicted along the eastern
edge of the site along the San Francisco Bay. Two to three additional small structures are located further inland north of
the San Bruno Canal; a small roadway originating west of the proposed project site leads to these structures. Land
immediately adjacent to the proposed project site is also primarily vacant and undeveloped.
1947 The proposed project site is primarily vacant undeveloped land. A small roadway around the perimeter of the site, as well
as one or two through the site, is now present. The San Bruno Canal is not designated. Several additional small
structures are now present south and east of the proposed project site. The project site area is designated as Point San
Bruno, and Oyster Point is now designated further north of the proposed project site. Land immediately adjacent to the
proposed project site is also primarily vacant and undeveloped.
1956 The proposed project site is primarily vacant undeveloped land, however, is now designated as being occupied by the
California National Guard. A larger roadway now leads to the center of the site where fifteen small structures are
depicted. Another large roadway traverses south of the proposed project site along the San Francisco Bay to an area
where a complex of large structures now exists. The project site area is still designated as Point San Bruno, and Oyster
Point is now designated further north of the proposed project site. A “channel” and “spoil area” are designated in the San
Francisco Bay south-southeast of the proposed project site. Land immediately adjacent to the proposed project site to the
north and east is still primarily vacant and undeveloped.
1956
The proposed project site appears similar to the way it did in 1956, however, the large roadway that led to the center of
tothe site is now shorter, and fourteen of the fifteen small structures are no longer present. The now shorter roadway leads
1968
to the one remaining structure that is designated as a “Radio Tower.” The proposed project site area is still designated as
being occupied by the California National Guard. The large roadway that traversed south of the proposed project site
along the San Francisco Bay is also now shorter and some of the previous structures part of the complex have been
replaced with new structures slightly north. Other features in the immediate vicinity of the proposed project site are similar
to how they were in 1956, except that a “marina” now occupies the area just south of Oyster Point (north of the proposed
project site). Land immediately adjacent to the proposed project site to the north and east is still primarily vacant and
undeveloped.
1956
The roadways and structures that occupied the proposed project site in the 1956–1968 topographic map are present. The
toproposed project site area is still designated as being occupied by the California National Guard. A new large roadway
1973now appears along the western and northern perimeter of the site. Additionally, several large structures now occupy the
western and northern areas of the proposed project site. Areas of the San Francisco Bay and San Bruno Canal, located
south of the site, are now occupied by land. This land cuts through the “channel” that is designated to exist in the San
Francisco Bay, and the San Bruno Canal is no longer present. Land at the northern end of the site also now occupies a
larger area where water previously occurred. Land immediately adjacent to the proposed project site to the north and east
are now occupied by structures and roadways.
1993 The proposed project site appears similar to the way it does today. It is occupied by a similar network of roadways and
structures that exist at the Genentech facility. The area is still designated as Point San Bruno, and Oyster Point and the
Marina are present further north. Areas surrounding the proposed project site are also fully developed.
SOURCE: Environmental Data Resources, Inc., EDR Historical Topographic Map Report, March 22, 2006.
Environmental, Health and Safety (EHS) Protection Policy
In striving to conduct their business in an environmentally responsible manner and protect the health
and safety of their employees, Genentech adheres to an Environmental, Health and Safety (EHS)
Protection Policy that includes policy objectives in each of the following areas:
Workplace Safety (conduct operations in a manner that fosters safety)
Environmental Protection (employ practices to reduce reliance on hazardous materials)
Integration into Business Decisions
Compliance (comply with EHS regulations)
Emergency Preparedness
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Table 4.6-2 Historical Aerial Photograph Information
1946 The proposed project site is primarily vacant undeveloped land. A large roadway leads to the center of the site which is
occupied by several small structures. Another large roadway traverses south of the proposed project site along the San
Francisco Bay to an area where a complex of large structures exists. Land immediately adjacent to the proposed project
site to the north is still primarily vacant and undeveloped. Land located further east is occupied by large roadways and
structures.
1956 The proposed project site and surrounding areas appear similar to the way they were in 1946, except that the roadway
leading to the center of the site is now longer and ends at a larger complex of smaller structures. Similarly, the large
roadway that traverses south of the proposed project site along the San Francisco Bay now leads to a denser complex of
buildings. Areas to the north and east are similar to the way they were in 1946.
1965 The proposed project site is now further developed with large building complexes, parking lots and a few water towers. The
development is primarily growing along the southern and eastern ends of the proposed project site. Several parcel of
graded vacant land are also now present. Several new roadways also now appear at the northern end of the site. Areas to
the north and east are similar to the way they were in 1956.
1973 The majority of the proposed project site is developed with roadways, buildings, parking lots and a few water towers. Large
parcels of graded vacant land exist at the center, northeastern and southern areas of the site. Areas to the north and east
are also more developed with structures and roadways.
1982 The proposed project site appears similar to the way it does today. It is occupied by a similar network of roadways and
structures that exist at the Genentech facility. Areas surrounding the proposed project site are also fully developed.
1993 The proposed project site appears similar to the way it did in 1982, except with a few additional structures present. It is
occupied by a similar network of roadways and structures that exist at the current Genentech facility. Areas surrounding the
proposed project site are also fully developed.
SOURCE: Environmental Data Resources, Inc., EDR Historical Topographic Map Report, March 22, 2006.
Supply Chain Management (encourage suppliers, contractors, and partners to comply with EHS
regulations, and minimize the use of toxic chemicals and the generation of hazardous wastes)
Industry Responsibility (standards to assure biological agents do not adversely affect human health
or the environment)
Continuous Improvement
Employees
Hazardous Materials Practices
Hazardous materials used by Genentech principally relate to research, development and manufacturing
of biotechnology products, and could include the following:
Solvents used for cleaning, extraction, or other laboratory and production activities
Reagents (chemical starting materials)
Chemical reaction products, which may have unknown compositions
Radioisotopes (radioactive elements used to stimulate or trace chemical reactions)
Infectious agents, including bacteria, viruses, and other medical wastes
Test samples (e.g., specimens such as blood, tissue, soil, or water), prior to use in a testing
procedure
Wastewater neutralization chemicals
Chemicals used to clean process equipment
Genentech?s manufacturing processes use recombinant DNA (rDNA) technology to grow medicinal
proteins from cells. Depending on the size and complexity of the protein, the manufacturing process
uses biological materials. Because of the low environmental and health risk associated with
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manufacturing proteins with biological materials, there are no standard requirements to manage
biological wastes in a particular manner. Biological waste effluents at Genentech facilities are currently
inactivated through either heat or chemical processes.
In recent years Genentech has become involved in small molecule and antibody conjugation research and
development activities. These programs, common in the biopharma sector, frequently involve newly
developed chemicals for which there is limited research and data regarding hazardous properties and
effects. Genentech takes a conservative approach by managing these substances as toxic even if they
have not been proven to be toxic. Genentech incorporates specific containment and ventilation design
features into laboratories intended for small molecule or antibody conjugate research, and provides
appropriate personal protective equipment for lab workers in these areas.
Maintenance of the Genentech Campus, as well as proposed construction activities, also requires the use
of hazardous materials. Examples of hazardous materials involved in vehicle, grounds, and building
maintenance, or used on construction sites, include the following:
Fuels (gasoline and diesel)
Oils and lubricants
Antifreeze
Cleaners, which may include solvents and corrosives in addition to soaps and detergents
Paints and paint thinners (latex)
Freons (refrigerants)
Pesticides and herbicides
Genentech has a variety of programs in place to ensure ongoing compliance with regulatory requirements
governing the management of hazardous materials. Genentech has a combined Storm Water Pollution
Prevention Plan and Spill Prevention Control and Countermeasure Plan to manage the potential risks
associated with an accidental release of hazardous materials to storm drains. Stormwater is monitored
regularly consistent with regulatory requirements. The Genentech Chemical Hygiene Plan describes the
company?s laboratory safety program, and applies to all employees engaged in the use of hazardous
chemicals in laboratories. The Chemical Hygiene Plan sets forth requirements and accountability for the
proper labeling of all laboratory chemicals, the provision of appropriate training for lab personnel, the
provision of appropriate protective equipment, and the implementation of periodic inspections.
Genentech has a comprehensive Biosafety Program designed to protect employees against
occupationally-acquired infections, to prevent environmental releases of biohazardous materials and
wastes, and to ensure compliance with regulations and guidelines applicable to biological materials. The
Biosafety Program consists of several components, including the Genentech Institutional Biosafety
Committee, the Biosafety Manual, the Medical Surveillance Program, and the Bloodborne Pathogens
Program (including Exposure Control Plan). Genentech has a comprehensive Laboratory Waste
Management Guide providing detailed information and resources to laboratory personnel regarding the
precise protocols for management of laboratory waste streams that may be hazardous, including
radioactive waste, biohazardous waste, laboratory chemical waste, and non-chemical solid wastes. In
addition, Genentech has created an Institutional Biosafety Committee and a Radiation Safety Committee
to oversee compliance efforts and practices where biohazardous and radioactive materials may be used,
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as well as a Research and Process Development EH&S Oversight Committee to oversee all EH&S issues
pertaining to research laboratory and process development activities
Genentech has an Injury & Illness Prevention Program, as well as a Hazard Communication Program, to
ensure that employees are aware of any workplace hazards as well as the applicable hazardous materials
management requirements. EH&S training courses are provided to employees based on their job duties
and responsibilities pertaining to hazardous materials and/or wastes. Genentech maintains a company
?intranet?, on which the EH&S Department maintains all relevant company programs, procedures,
standards, and general information and resources for employees. In addition to the EH&S information
available on Genentech?s intranet, the company maintains a database of MSDS? for chemicals used onsite
that is accessible by all employees.
Genentech?s Health Services Department manages a Medical Surveillance Program to identify
individuals? health conditions that warrant special attention for work exposures and to detect early
possible effects of potentially harmful work exposure. Personal monitoring devices (such as dosimetry
badges, finger rings, organic vapor monitors, sampling tubes and cartridges and direct reading
instruments) are employed to conduct work area and employee monitoring.
The following describe hazardous materials located or potentially located at the Genentech Campus in
broad categories: general chemicals, underground storage tanks, hazardous materials sites, infrastructure
(e.g., asbestos, lead, polychlorinated biphenyls, and mercury), radioactive materials, and biohazardous
materials.
General Chemicals
Many chemical materials, some hazardous, are used for research and production activities, as well as
facilities maintenance, during the course of daily operations at Genentech. Virtually all of the buildings
on the Genentech Campus contain commercial products (e.g., cleaners, copier toners, etc.) that could be
considered ?hazardous materials? under regulatory definitions. Non-household-type hazardous materials
used in research laboratories include chemical reagents, solvents, radioisotopes, and biohazardous
substances.
Process equipment may be cleaned using chemicals such as potassium hydroxide and phosphoric acid.
Onsite wastewater neutralization systems may use sulfuric acid and sodium hydroxide. Diesel fuel is used
across the Genentech Campus for emergency power generators. For certain product lines, Genentech
uses Tetramethylammonium chloride (TMAC) to extract medicinal proteins out of the water at the end
of a production process. Some forms of TMAC waste streams are considered to be hazardous by
California, but not by other jurisdictions. In terms of weight, TMAC is the largest single hazardous waste
stream produced by Genentech. During 2004, Genentech produced 329 metric tons of TMAC
hazardous waste as a result of using a chemical material to extract medicinal proteins from water at the
end of a production process for certain product lines.
Genentech?s South San Francisco Campus uses alcohol-based solvent products, primarily for production
cleaning purposes. These products include are alcohol wipes solution (70 percent alcohol/30 percent
water) and reagent alcohol. The solvent types represented are ethanol, methanol and iso-propanol.
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Maintenance units, including grounds, custodian services, and pest management use a wide variety of
commercial products formulated with hazardous materials. These include fuels, cleaners and degreasers,
solvents, paints, lubricants, pesticides and herbicides, adhesives, and sealers.
Underground Storage Tanks (USTs)/Hazardous Materials Sites
The potential exists for buildings or sites that would be affected by project development to have been
contaminated by hazardous substances as a result of former uses of the sites, leaks from unidentified
USTs, or unidentified buried debris that could contain hazardous substances or hazardous by-products.
Contaminated soils, building materials, and/or groundwater pose potential hazards to construction
workers, Genentech staff, and nearby employees if not managed and remediated safely. According to the
Environmental Data Resources Report, which lists whether or not any USTs occupy the proposed
project site, there are either active or inactive USTs at Genentech. Additionally, the proposed project site
is listed as a hazardous materials site in the Report. A more detailed discussion of this is provided below
under the summary of the Environmental Data Resources Report findings.
Infrastructure
Asbestos
Asbestos, a naturally occurring fibrous material, was used for years in many building materials for its
fireproofing and insulating properties. Loose insulation, ceiling panels, and brittle plaster are potential
sources of friable (easily crumbled) asbestos. In addition, underground utility tunnels may also contain
asbestos. Non-friable asbestos is generally bound to other materials such that it does not become
airborne under normal conditions. Any activity that involves cutting, grinding, or drilling during building
renovation or demolition or relocation of underground utilities could release friable asbestos fibers unless
proper precautions are taken. Inhalation of airborne fibers is the primary mode of asbestos entry into the
body, making friable materials the greatest potential health risk. Asbestos-related health problems include
lung cancer and asbestosis.
In accordance with Sections 25915 through 25916 of the California Health and Safety Code, a facility-
wide inventory of locations of asbestos-containing building materials must be maintained and annual
facility -wide notification of locations containing asbestos must be provided. Appropriate signs are
posted when asbestos-containing materials are disturbed during construction or renovation at facility
locations, in accordance with State and Bay Area Air Quality Management District regulations.
Lead
Lead is a naturally occurring metallic element. Among its numerous uses and sources, lead can be found
in paint, water pipes, solder in plumbing systems, and soils around buildings and structures painted with
lead-based paint. In 1978, the federal government required the reduction of lead in house paint to less
than 0.06 percent (600 parts per million). However, some paints manufactured after 1978 for industrial
uses or marine uses legally contain more than 0.06 percent lead. Because some structures within the
MEIR Study Area were constructed prior to 1978, wall surfaces and other building materials may contain
lead-based paints, which can pose a risk of exposure due to chipped or peeling paint, or from renovation
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or demolition of buildings or building materials that contain lead. Excessive exposure to lead (even low
levels of lead) can result in the accumulation of lead in the blood, soft tissues, and bones.
Polychlorinated Biphenyls (PCBs)
PCBs are organic chemicals, usually in the form of oil, that were formerly used in electrical equipment,
including transformers and capacitors, primarily as electrical insulators. Some PCB-containing electrical
equipment (e.g., transformers and capacitors) may still be present within the MEIR Study Area. In
addition, some fluorescent light ballasts that contain PCBs could also be present in existing buildings that
would be demolished or renovated under the proposed project. Nearly all ballasts manufactured prior to
1979 contain PCBs. Ballasts manufactured after July 1, 1978, which do not contain PCBs, are required to
be clearly marked "No PCBs." PCBs, which are highly persistent in the environment, can cause various
human health effects, including liver injury, irritation of the skin and mucous membranes, and adverse
reproductive effects. PCBs are also suspected human carcinogens. In California, PCB-containing
materials must be disposed of as hazardous waste.
Mercury
Elemental mercury is an insoluble, liquid, inorganic metal. It is commonly used in laboratory and medical
equipment such as thermometers and manometers (used for measuring pressure). Other uses include
electrical equipment and some water pumps. Mercury liquid evaporates very slowly if exposed to air. At
certain levels of exposure, mercury vapors are toxic and can cause kidney and liver damage. It is possible
that elemental mercury may be present in research laboratory sink traps, in cupboard floor spaces, or in
sewer pipes if there have been any historical accidental spills or releases prior to the adoption of more
stringent environmental regulations pertaining to hazardous waste disposal. If such spills or releases had
occurred, exposure could result in the event of building renovation or demolition.
Radioactive Materials
Radioactive substances contain atoms that spontaneously emit radiation from the transformation of
unstable atomic nuclei, which result in chemically different substances that may or may not be
radioactive. Radioactive atoms are called ?radionuclides? or ?radioisotopes.? Because radioactive
materials emit ionizing radiation, their presence can be detected easily. Researchers and health care
professionals take advantage of this easy detectability by using radioactive materials to study various
biochemical functions in animals and humans. Radiopharmaceuticals (radioisotopes or drugs containing
radioisotopes) are also used in medicine and research. Limited types and quantities of radioisotopes are
also used in research laboratories. All radioisotopes used on the project site are stored in sealed
containers designed to prevent release of radioactive materials to the environment.
Exposure to ionizing radiation can result in adverse human health effects that range from short-term
mild symptoms (such as sunburn) to serious illness or death, depending upon the amount and
concentration of the radioactive source and the duration of the exposure. The extent to which exposure
would result in any adverse effects depends on the radioisotope and the amount and duration of
exposure.
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For wastes that are longer-lived, the final disposal depends on the hazard class of the low-level
radioactive waste (LLRW). Genentech collects, prepares, and packages all radioactive waste for shipment
and disposal. Genentech generates radioactive waste classified as Class A waste. Class A is waste that is
usually segregated from other waste classes at the disposal site. Genentech uses a licensed radioactive
waste broker (Philotechnics) to transport all radioactive waste to licensed disposal facilities. The two
primary disposal facilities used by Genentech are the Energy Solutions facility in Salt Lake City, Utah and
the Pecos facility located in Richland, Washington.
Biohazardous Materials
By statutory definition, biohazardous materials include biohazardous laboratory wastes and biologic
specimens such as human or animal tissue, as defined by Section 117635 of the California Health and
Safety Code.
Genentech has developed programs, practices, and procedures for monitoring, routine inspection,
reporting, and waste management to reduce community and worker exposure to potential hazards
associated with medical wastes and biological hazards. Activities that could create biohazardous aerosols
are conducted in biosafety cabinets, which filter all released air to remove biohazardous materials.
Biosafety cabinets are tested annually in accordance with regulatory requirements. Regulations specify
that medical waste is stored in refrigerated facilities for not more than 90 days and that such waste is
properly packaged and labeled. Medical waste may also be rendered noninfectious through steam
sterilization. Genentech uses a medical waste transporter (e.g., Stericycle) to transport and treat all
medical wastes, which are subsequently disposed of in municipal landfills.
Disposal of Hazardous Materials Generated On-Site
The Genentech Campus is registered with the U.S. Environmental Protection Agency (EPA) as a
generator of hazardous waste. Genentech does not store (for longer than 90 days) or dispose of
hazardous chemical waste on site. In most cases, the waste is picked up from a collection location or
generator site where the recycling or disposal process for that waste is managed. Before the waste is
collected, it must be packaged and labeled properly, which includes segregating incompatible materials,
and placing them in appropriate sealed containers. Chemical wastes are further segregated by type, and
consolidated, bulked, or compacted before a licensed hauler transports them from the Genentech
Campus to permitted off-site facilities for incineration, treatment, recycling, or other disposal.
Hazardous waste is disposed of at licensed disposal facilities in California and other states. While
municipal landfills were once the most common destination for hazardous waste, federal (1984
Amendments to the Resource Conservation and Recovery Act [RCRA]) and state (Hazardous Waste Control)
law now bans their use for many of the most commonly generated hazardous wastes. Alternative
treatment and disposal technologies, including incineration and recycling, are now more common
methods of disposing of hazardous wastes.
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Hazardous Materials Transportation Requirements
Genentech contracts with licensed hazardous waste transporters to transport hazardous wastes sent off
site for treatment or disposal at licensed hazardous waste facilities. Hazardous materials are routinely
transported by truck or rail. The U.S. Department of Transportation (USDOT), Office of Hazardous
Materials Safety, prescribes strict regulations for the safe transportation of hazardous materials, as
outlined in Title 49 of the Code of Federal Regulations. In California, the California Highway Patrol
(CHP) has the primary responsibility for enforcing federal and state regulations and responding to
hazardous materials transportation emergencies. Specifically, Section 31303 of the California Vehicle
Code requires that when hazardous materials are transported on state or interstate highways, the
highway(s) that offer the shortest overall transit time possible shall be used. Transportation of hazardous
materials along any city or state roadways within or near the facility is subject to all hazardous materials
transportation regulations established by the California Highway Patrol.
Genentech's Compliance History
According to Genentech's 2004 Corporate Environmental Performance Report, Genentech?s South San
Francisco facility received four Notices of Violation (NOVs) during 2004 as follows:
One wastewater NOV was received for low pH in wastewater discharged to the sewer system. This
exceedance was discovered during routine monitoring performed by Genentech. A root cause
analysis was conducted, and the cause of the exceedance was determined to be improper operation
of a particular piece of equipment. The users of that equipment were re-trained on proper
operation and drain disposal.
Two wastewater NOVs were received for exceeding sulfide limits in wastewater discharged to the
sewer system. These exceedances were discovered during routine monitoring by the local
government. A root cause analysis was conducted, and although several potential causes were ruled
out, no exact cause was conclusively determined. The facility continues to monitor for potential
recurrence.
One air emissions NOV was received for exceedance of usage limits of solvent products in
cleaning operations. The facility was permitted to use 23,820 pounds (lbs) in a 12 month period,
and used 26,749 lbs in the period 4/1/2003 through 4/1/2004. This resulted in a fine of $1,000.
The facility evaluated its operations and concluded that the original permit limit was inadequate to
meet recent expansions in production at the facility. The facility applied for and was granted a
higher limit for solvent usage in its air permit. The facility also improved its system for tracking
solvent usage, to prevent exceedances in the future.
Hazardous Materials Summary (2005)
Table 4.6-3 below outlines hazardous materials quantities utilized at the existing Genentech Campus for
the year 2005.
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Table 4.6-3 2005 Hazardous Materials Summary at Genentech by Campus
Lower Campus Upper Campus Middle Campus West Campus
Total (Pounds (lbs.))
551,600 lbs. 62,500 lbs. 270,000 lbs. 11,500 lbs.
Non-Waste Materials Reported*
Combustible 345,600 lbs. 54,000 lbs. 135,200 lbs. 11,500 lbs.
a
Flammable 37,600 lbs. 7,500 lbs. 73,700 lbs. 0 lbs.
Corrosive 180,300 lbs. 4,300 lbs. 53,000 lbs. 0 lbs.
b
Reactives 220 lbs. 15 lbs. 1,500 lbs. 0 lbs.
c
Toxics 52,000 lbs. 1,500 lbs. 40,300 lbs. 0 lbs.
Radioactives (Curies [Ci]) 0.01 Ci 943 Ci 2,800 Ci 0 Ci
Waste Categories
Hazardous Waste-Aqueous 26,900 lbs. 20 lbs. 16,400 lbs. 0 lbs.
d
Hazardous Waste-Flammable 3,200 lbs. 0 lbs. 38,000 lbs. 0 lbs.
Hazardous Waste-Lab pack 11,100 lbs. 950 lbs. 3,900 lbs. 0 lbs.
e
Medical Waste 3,500 lbs. 1,500 lbs. 5,000 lbs. 0 lbs.
Radioactive Waste 700 lbs. 700 lbs. 4,100 lbs. 0 lbs.
f
Broken Glassware Waste (Campus-Wide) 3,000 lbs.
SOURCE: Harnish 2005
Liquids listed in pounds (lbs.) assumes 1 Gallon = 10 lbs.
* Materials listed with multiple hazards are subtotaled under each hazard class. For example, 1 lb. Sodium azide would be included as 1 lb. under
both the toxic and reactive classifications. Due to this overlapping reporting, the quantities for each category cannot simply be added together to
derive the total aggregate quantity of hazardous materials. The ?total? row reflects the true total of materials on each campus neighborhood on any
given day, without double-counting for overlapping categories. Thus, in the ?total row, 1 lb. Sodium azide would be reflected as 1 lb.
a. The combustible classification includes 50,115 gallons (501,150 lbs.) of diesel fuel in aboveground tanks used for emergency generation.
b. Includes both acids and bases.
c. Includes explosives, Class 3/4 Oxidizers, Class 2/3 Water Reactives, and other highly reactive materials.
d. Aqueous waste typically contains 50% toxics.
e. Lab-pack waste typically contains 40% toxics, 40% flammables, 15% corrosives, and 5% reactives.
f. Radioactive waste is estimated from 2005 Waste Manifests totaling 5,500 lbs. for the year for all of the South San Francisco campus. It is assumed
that 75% of radioactive waste is generated from the Middle Campus and the remaining waste is generated equally between the Lower and Upper
Campus Labs.
Environmental Data Resources (EDR) Report
Environmental Data Resources (EDR) performed a records check in March 2006 of federal, state, and
county hazardous waste lists compiled pursuant to Section 65962.5 of the Government Code, as required
by Public Resources Code Section 21092.6, including, but not limited to, the Leaking Underground
Storage Tanks (LUST) List, the Hazardous Waste Substance List (Cortese list), the Emergency Response
Notification System (ERNS), and registered small or large hazardous waste generators. The records
check was done for the approximate address of ?1000 Grandview Drive?, however was reviewed for the
following addresses that were a part of the EIR Study Application (filed in September 2005 with the City
of South San Francisco):
1. 1 DNA Way
2. 342 Allerton Avenue
3. 410 Allerton Avenue
4. 444 Allerton Avenue
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5. 400-428 Grandview Drive
6. 448 Grandview Drive
7. 425 Grandview Drive
8. 560 Forbes Boulevard
9. 301 East Grand Avenue
10. 345 East Grand Avenue
According to the EDR, the Genentech, Inc. property located at 460 Point San Bruno Boulevard is
included on the following lists: (1) federal list of RCRA large quantity generator of hazardous wastes; (2)
the California Water Resources Control Board?s list for having a waste discharge system; (3) the
California Facility Inventory Database, which lists active and inactive UST locations; and (4) the Air
Resources Board?s Emissions Inventory Data list for sites with toxics and criteria pollutant air emissions.
Additionally, the portion of the Genentech facility located at 1 DNA Way was listed as having registered
above ground storage tanks (AST). The portion of the Genentech facility located at 1200 Grandview
Drive was listed by San Mateo County as being a hazardous waste generator. Overall, the EDR Report
identified the following as being located within -mile of 1000 Grandview Drive:
1 RCRA Large Quantity Generators (LQG) of hazardous wastes
8 RCRA Small Quantity Generators (SQG) of hazardous wastes
6 Emergency Response and Notification System (ERNS) sites
521 Hazardous Materials Incident Report System (HRMIS) sites
1 Toxic Substances Control Act (TSCA) list
9 Facility Index System (FIS) list
2 California Water Resources Control Board?s list
2 Cortese list
3 Leaking Underground Storage Tank (LUST) list
2 California Facility Inventory Database (FID) for USTs
4 Historical Registered UST Database
3 Statewide Environmental Evaluation and Planning System (SWEEPS) UST list
6 California Hazardous Material Incident Report System
23 San Mateo County Hazardous Waste Sites list
14 HANET list
5 Air Resources Board?s Emissions Inventory Data EMI list
The following three LUST cases located within -mile of the proposed project site have all been closed:
(1) Tornberg Enterprises located at 1776 Grandview Drive; (2) United Parcel Service located at 657
Forbes Boulevard; and (3) Yellow Freight System, Inc. located at 201 Haskins Way.
More generally, based on the historical industrial use of the area, it is possible that soil and/or
groundwater contaminated with petroleum hydrocarbons, metals, solvents, or other industrial materials
could be encountered during construction activities. Known historical contamination includes leaks from
underground storage tanks, which have been managed effectively in accordance with regulatory
requirements. Low concentrations of ammonia were discovered in soil and groundwater under a building
on lower campus, for which the Regional Water Quality Control Board issued a "No Further Action"
letter in 2003. Naturally occurring asbestos in serpentine rock is known to be present in the middle
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campus area, and possibly other areas on campus. If any contaminated soil and/or groundwater is
encountered during construction, it will be managed in accordance with mitigation measure 4.6-1 and all
applicable regulatory requirements
Emergency Response
Genentech?s Emergency Response Procedures
Genentech emergency response procedures are outlined in Genentech?s Integrated Contingency Plan,
incorporating the Core Plan: Emergency Response Procedures at Genentech?s South San Francisco Site.
This document outlines reporting, assessment, commencement of the Incident Command System, Plan
implementation, training, clean-up, decontamination, and follow-up actions in the event of an accidental
release or other emergency involving hazardous materials. This document is maintained on file at the San
Mateo County Health Department?Environmental Health Division (SMCEHD). Principal
responsibility for emergency response at Genentech lies with the First Alert Team (FAT). The FAT is
staffed by members from the Corporate Facilities Services, Security, EH&S, and Occupational Health
Services groups.
South San Francisco Fire Department Emergency Response
According to the City of South San Francisco Fire Department (SSFFD), the City does not have any
specific emergency responses unique to Genentech. The SSFFD responds to emergencies based on
incident type and adjusts response depending on the circumstances on the scene at the time of the
incident.
4.6.2Regulatory Framework
The management of hazardous materials and hazardous wastes, including chemicals, radioactive
materials, and biohazardous materials, is subject to numerous laws and regulations at all levels of
government. These laws apply to research activities, operations and maintenance work, and other
activities at the Genentech site. Summaries of federal and state laws and regulations related to hazardous
materials management are presented below. California law allows for certain hazardous materials
regulatory programs, including those pertaining to USTs, hazardous materials storage, and hazardous
materials management, to be delegated to local agencies.
Federal
Federal and state laws require detailed planning to ensure that hazardous materials are properly handled,
used, stored, and disposed of, and, in the event that such materials are accidentally released, to prevent or
to mitigate injury to health or the environment. Primary federal agencies with responsibility for
hazardous materials management include the Environmental Protection Agency (EPA), Department of
Labor (Federal Occupational Health and Safety Administration [OSHA]), Department of Transportation
(DOT), and Nuclear Regulatory Commission (NRC). Major federal laws and issue areas include the
following statutes (and regulations promulgated thereunder):
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Resource Conservation and Recovery Act (RCRA)
Hazardous and Solid Waste Amendments Act (HSWA)
Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA)
Superfund Amendments and Reauthorization Act (SARA)
Emergency Planning and Community Right-to-Know (SARA Title III)
State
Primary state agencies with jurisdiction over hazardous chemical materials management are the
Department of Toxic Substances Control (DTSC) and the Regional Water Quality Control Board
(RWQCB). Other state agencies involved in hazardous materials management are Cal/OSHA, the
Department of Industrial Relations (State OSHA implementation), State Office of Emergency Services
(OES?California Accidental Release Prevention implementation), California Department of Fish and
Game (CDFG), California Air Resources Board (CARB), California Highway Patrol (CHP), State Office
of Environmental Health Hazard Assessment (OEHHA?Proposition 65 implementation) and
California Integrated Waste Management Board (CIWMB).
Hazardous chemical and biohazardous materials management laws in California include the following
statutes (and regulations promulgated there under):
Hazardous Waste Control Law
Safe Drinking Water and Toxic Enforcement Act of 1986 ("Proposition 65?)
Carpenter-Presley-Tanner Hazardous Substances Account Act
Hazardous Waste Management Planning and Facility Siting ("Tanner Act")
Hazardous Materials Release Response Plan and Inventory Law of 1985 (Business Plan Act)
California Medical Waste Management Act
Local
The primary local agency, known as the Certified Unified Program Agency (CUPA), with responsibility
for implementing federal and state laws and regulations pertaining to hazardous materials management is
San Mateo County Health Department, Environmental Health Division. The Unified Program is the
consolidation of six state environmental regulatory programs into one program under the authority of a
CUPA. A CUPA is a local agency that has been certified by Cal EPA to implement the six state
environmental programs within the local agency's jurisdiction. This program was established under the
amendments to the California Health and Safety Code made by SB 1082 in 1994. The six consolidated
programs are:
Hazardous Materials Release Response Plan and Inventory (Business Plans)
CalARP
Hazardous Waste (including Tiered Permitting)
Underground Storage Tanks
Above Ground Storage Tanks (SPCC requirements)
UFC Article 80 HMMP and HMIS
As the CUPA for the County of San Mateo, the San Mateo County Health Department, Environmental
Health Division maintains the records regarding location and status of hazardous materials sites in the
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county and administers programs that regulate and enforce the transport, use, storage, manufacturing,
and remediation of hazardous materials. By designating a CUPA, San Mateo County has accurate and
adequate information to plan for emergencies and/or disasters and to plan for public and firefighter
safety.
A Participating Agency (PA) is a local agency that has been designated by the local CUPA to administer
one or more Unified Programs within their jurisdiction on behalf of the CUPA. The City of South San
Francisco Fire Department maintains a special program that regulates hazardous materials through
disclosure and risk management plans as well as above ground storage tank referral in cooperation with
the County of San Mateo. Thus, the City of South San Francisco Fire Department is a PA with the San
Mateo County Health Department, Environmental Health Division as the CUPA.
Regulations
Medical Waste Regulations
The United States Department of Health and Human Services (USDHHS), Centers for Disease Control
and Prevention, and National Institutes of Health prescribe containment and handling practices for use
in microbiological, biomedical, and animal laboratories. All Genentech laboratories follow the mandated
hygienic practices. Based on the potential for transmitting biological agents, the rate of transmission of
these agents, and the quality and concentrations of biological agents produced at a laboratory, Biosafety
Levels are defined for four tiers of relative hazards. Biosafety Level 1 is for the least hazardous biological
agents, and Biosafety Level 4 is for the most hazardous biological agents. Biosafety Levels for infectious
agents are based on the characteristics of the agent (virulence, ability to cause disease, routes of exposure,
biological stability, and communicability), the quantity and concentration of the agent, the procedures to
be followed in the laboratory, and the availability of therapeutic measures and vaccines.
Federal and state laws, such as the Animal Welfare Act, specify standards for record keeping and the
registration, handling, care, treatment, and transportation of animals. Such laws are enforced by the U.S.
Department of Agriculture and the California Department of Health Services (DHS). Further,
Genentech programs, practices, and procedures previously described for monitoring, routine inspection,
reporting, and waste management have been developed to reduce potential community and worker
exposure to hazards associated with the use of animals in research.
Medical wastes must be managed as a biohazardous material, in accordance with Section 117635 of the
California Health and Safety Code. The management of biohazardous materials must comply with
USDHHS guidelines and DHS regulations pertaining to such materials. Biohazardous medical waste is
generally regulated in the same manner as hazardous waste, except that special provisions apply to
storage, disinfection, containment, and transportation. The DHS Medical Waste Management Program
enforces the Medical Waste Management Act and related regulations.
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RadioactiveMaterialsRegulations
The Atomic Energy Act (42 U.S.C. Sections 2011?2259) (AEA) ensures the proper management of source,
special nuclear, and by-product material. The AEA, and the statutes that amended it, delegate the control
of nuclear energy primarily to the Department of Energy, the Nuclear Regulatory Commission, and the
United States Environmental Protection Agency (EPA). The California Radiation Control Law
(California Health & Safety Code Sections 114960?114985) is a regulatory program designed to provide
for compatibility with the standards and regulatory programs of the federal government and integrate an
effective system of regulation within the state. The program regulates sources of ionizing radiation and
establishes procedures for performance of certain regulatory responsibilities with respect to the use and
regulation of radiation sources. These laws and regulations govern the receipt, storage, use,
transportation, and disposal of sources of ionizing radiation (radioactive material) and protect the users
of these materials and the general public from radiation hazards.
The use of radioactive materials at the Genentech site is specifically subject to the conditions of a
radioactive materials license issued and administered by the Radiologic Health Branch of the DHS.
Genentech administers and monitors facility compliance with license requirements. Radioactive materials
licensing requirements include routine inspection and monitoring of areas where radioactive materials are
used to ensure that surfaces are not contaminated with radioactivity above background levels. Under the
radioactive materials license, renovation or demolition of facilities using radioactive material requires
decommissioning of the facilities. This involves radiation testing and conducting decontamination and
waste handling activities in accordance with applicable regulations.
Operational and Disposal Regulations
Worker Safety
The California Occupational Safety and Health Administration (Cal/OSHA) and the federal
Occupational Safety and Health Administration are the agencies responsible for ensuring worker safety in
the handling and use of chemicals in the workplace. In California, Cal/OSHA assumes primary
responsibility for developing and enforcing standards for safe workplaces and work practices.
Hazardous Waste Handling
Cal-EPA and DTSC regulate the generation, transportation, treatment, storage, and disposal of
hazardous waste under RCRA and the California Hazardous Waste Control Law. Both laws impose
?cradle-to-grave? regulatory systems for handling hazardous waste in a manner designed to protect
human health and the environment.
Asbestos Regulations
The Clean Air Act regulates asbestos as a hazardous air pollutant, which subjects it to regulation by
BAAQMD under its Regulation 11, Rule 2. OSHA also regulates asbestos as a potential worker safety
hazard. These rules and regulations prohibit emissions of asbestos from demolition or construction
activities, require medical examinations and monitoring of employees engaged in activities that could
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disturb asbestos, mandate precautions and safe work practices to reduce the potential for release of
asbestos fibers, and require notice to federal and local government agencies prior to renovation or
demolition activities that could disturb asbestos.
Lead Regulations
Because of its toxic properties, lead is regulated as a hazardous material. Lead is also regulated as a toxic
air contaminant. State-certified contractors must perform inspection, testing, and removal (abatement) of
lead-containing building materials in compliance with applicable health and safety and hazardous
materials regulations.
Hazardous Materials Transportation
The USDOT prescribes strict regulations for the safe transportation of hazardous materials, including
requirements for hazardous waste containers and licensed haulers who transport hazardous waste on
public roads.
Emergency Response to Hazardous Materials Incidents
California has developed an Emergency Response Plan to coordinate emergency services provided by
federal, state, and local government and private entities. Response to hazardous materials incidents is one
component of this plan. The State Office of Emergency Services administers the plan, which coordinates
the responses of other agencies, including Cal-EPA, CHP, California Department of Fish and Game, the
Regional Water Quality Control Board (RWQCB), and the Radiologic Health Branch of the DHS.
Genentech will continue to implement the plan at the site, in cooperation with the South San Francisco
Fire Department.
4.6.3Project Impacts and Mitigation
Methodology
The analysis in this section focuses on the use, generation, disposal, transport, or management of
hazardous or potentially hazardous materials at the Genentech Campus. The volume of hazardous waste
generated by various Genentech activities is quantified for the year 2005, as described in Table 4.6-3.
Disposal options, the probability for risk of upset, and the severity of consequences to people or
property associated with the increased use, handling, transport, and/or disposal of hazardous materials
associated with implementation of the proposed project are analyzed. In order to determine if
implementation of the proposed project has the potential to result in development of a site that is
included on a list of hazardous material sites, EIP staff reviewed the EDR Report.
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Thresholds of Significance
The following thresholds of significance are based on Appendix G of the 2006 CEQA Guidelines. For
purposes of this MEIR, implementation of the proposed project could result in potentially significant
impacts from hazards and hazardous materials if the project would result in any of the following:
Create a significant hazard to the public or the environment through the routine transport, use, or
disposal of hazardous materials.
Create a significant hazard to the public or the environment through reasonably foreseeable upset
and accident conditions involving the release of hazardous materials into the environment.
Emit hazardous emissions or handle hazardous or acutely hazardous materials, substances or waste
within one-quarter mile of an existing or proposed school.
Be located on a site which is included on a list of hazardous materials sites compiled pursuant to
Government Code Section 65962.5 and, as a result, would it create a significant hazard to the
public or the environment.
For a project located within an airport land use plan or, where such a plan has not been adopted,
within two miles of a public airport or public use airport, would the project result in a safety hazard
for people residing or working in the project area.
For a project within the vicinity of a private airstrip, would the project resulting in a safety hazard
for people residing or working in the project area.
Impair implementation of or physical interference with an adopted emergency response plan or
emergency evacuation plan.
Expose people or structures to a significant risk of loss, injury or death involving wild land fires,
including where wild lands are adjacent to urbanized areas or where residences are intermixed with
wild lands.
Impacts and Mitigation Measures
Threshold Create a significant hazard to the public or the environment through the routine
transport, use, or disposal of hazardous materials.
Impact 4.6-1 Implementation of the proposed project would not expose Genentech
employees or the nearby public to significant hazards, due to the routine
transport, use, disposal, or storage of hazardous materials (including
less-
chemical, radioactive, and biohazardous waste). This is considered a
than-significant
impact.
Implementation of the proposed project will result in the development of additional laboratories and
other research facilities that would use, store, or require the transportation and disposal of hazardous
materials. While the amount and type of hazardous materials may vary over time with changes in research
and additions to hazardous materials lists, the general range and type of hazardous materials used on-site
is not expected to substantially change upon implementation of the project. Genentech will continue to
use materials, some of which are considered hazardous, during the course of daily operations. These
hazardous materials include many of the inorganic and organic chemicals, chemical reagents and reaction
products, solvents, mercury, lead, asbestos, radioisotopes, biohazards, fuels, oils, paints, cleansers, and
pesticides that are currently used in laboratory research, building and grounds maintenance and vehicle
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maintenance. In addition, the proposed project would result in an increase in the number of individuals
that work and visit the facility, which would increase the number of individuals potentially exposed to
hazardous materials.
The individuals most at risk due to increased hazardous materials use associated with implementation of
the proposed project would be those employees who work at locations where hazardous materials are
found, such as laboratories, production and maintenance facilities, or construction sites. Whether a
person exposed to a hazardous substance at one of these locations would suffer adverse health effects
depends upon a complex interaction of factors to determine the effects of exposure to hazardous
materials: the exposure pathway (the route by which a hazardous material enters the body); the amount
of material to which the person is exposed; the physical form (e.g., liquid, vapor) and characteristics (e.g.,
toxicity) of the material; the frequency and duration of exposure; and the individual's unique biological
characteristics, such as age, gender, weight, and general health. Adverse health effects from exposure to
hazardous materials may be short-term (acute) or long-term (chronic). Acute effects can include damage
to organs or systems in the body and possibly death. Chronic effects, which may result from long-term
exposure to a hazardous material, can also include organ or systemic damage, but chronic effects of
particular concern include birth defects, genetic damage, and cancer. Off-site hazardous materials
exposure would only reasonably occur through limited circumstances such as accidental spill or release
during transport or use.
Use of Chemical Materials
State, federal, and local regulations and Genentech programs, practices, and procedures, including the use
of safety equipment, ensures that the potential for worker and/or public exposure to hazardous materials
less than significant
from improper or unsafe activities, or from accidents, is , as demonstrated in the
following discussion.
To reduce the potential for exposure to airborne chemicals, workers take standard precautions, such as
working under fume hoods when using chemicals that could present exposure hazards. The chemical
fume hood is a critical health and safety control in the laboratory setting, ensuring an adequate level of
protection from the possible harmful affects of chemicals. Laboratory fume hoods are generally a box-
like structure open on one side. Air is drawn through the fume hood and discharged to an exterior
exhaust system through the roof of the facility. In addition, some fume hoods are equipped with air
cleaning devices. Proper use of fume hoods keeps indoor laboratory toxic air contaminants below the
suggested guidelines of the American Conference of Governmental Industrial Hygienists (Threshold
Limit Values) and OSHA legal limits (Permissible Exposure Levels).
To prevent exposure through skin contact, Genentech requires that protective clothing, such as
laboratory coats, gloves, and safety glasses be worn while handling hazardous materials. In addition,
proper washing after handling chemicals is required. Eating, drinking, and smoking are prohibited in
laboratories and other areas where hazardous materials are used. These procedures are disclosed to all
staff that work with hazardous materials, and this training increases the safety awareness of Genentech
employees and further reduces the risks of exposure to hazardous chemicals through inhalation,
absorption, ingestion, and injection. Should an accident occur that could cause an individual to be
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exposed to a hazardous material, required emergency equipment, including fire extinguishers, eyewashes,
and safety showers, are also available.
Cal/OSHA requires all institutions that use hazardous materials to implement a Hazard Communication
Program and train employees that use hazardous chemicals in the safe use of those materials. Genentech
implements all safety procedures and conducts safety programs to ensure that these procedures are
consistently followed. Genentech will continue to implement these (or equivalent) programs, practices,
and procedures and, as needed, these programs could be expanded.
Title 8 of the California Code of Regulations (Section 3203 of the General Industry Safety Orders) also
requires every California employer to have a written Injury and Illness Prevention Program to provide a
safe and healthful workplace. OSHA mandates methods of documenting, investigating, and controlling
accidents that result in skin penetration. Evidence presented during OSHA rule-making procedures
indicates that these programs and methods are effective in reducing the number and severity of injuries
and illness in the workplace.
Use of Radioactive Materials
Radioactive materials use at Genentech is monitored to ensure consistency with the requirements of the
radioactive materials license, which articulates standards to maintain exposure levels below applicable
legal standards, thereby protecting users of radioactive materials. Like all hazardous materials, the effects
of the routine use of radioactive materials are limited to areas where exposure may occur and decreases
substantially with distance. For this reason, the individuals most at risk would be those specially trained
in the use of radioactive materials, which would reduce the likelihood for accidental exposure through
improper handling techniques. Furthermore, all individuals who handle radioactive waste are required to
wear a personal monitor that determines their cumulative exposure to radiation. If the monitor indicates
that established safety levels might be exceeded, the individual will not be exposed to potential sources of
radiation until the monitor indicates that safety levels can be maintained.
In accordance with strict regulatory guidelines, Genentech collects, prepares, and packages its radioactive
waste which is then transported by Philotechnics to a regulated radioactive waste disposal facility. The
two primary disposal facilities used by Genentech are the Energy Solutions facility in Salt Lake City, Utah
and the Pecos facility located in Richland, Washington. Genentech?s programs, practices, and procedures
for handling radioactive materials in compliance with all established regulatory requirements would
less than significant
ensure that the potential for significant health and safety hazards remains .
Use of Biohazardous Materials
In handling biohazardous materials, Genentech follows guidelines promulgated by the USDHHS that
determine the level of safety precautions that must be used for four tiers of relative hazards. Biosafety
Level 1 is for the least hazardous biological agents, and Biosafety Level 4 is for the most hazardous
biological agents. Biosafety Levels for infectious agents are based on the characteristics of the agent
(virulence, ability to cause disease, routes of exposure, biological stability, and communicability), the
quantity and concentration of the agent, the procedures to be followed in the laboratory, and the
availability of therapeutic measures and vaccines. Biosafety Level 1 agents pose minimal or no known
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potential hazard to individuals and the environment. Biosafety Level 2 agents are considered to be of
ordinary potential hazard and may produce varying degrees of disease through accidental inoculation, but
may be effectively contained by ordinary laboratory techniques and specific laboratory equipment.
Biosafety Level 3 agents pose more substantial risks, and work with these agents must be conducted in
contained facilities for which air flow is directed into the laboratory and access is controlled separately
from public areas.
Occupational and public safety is protected by selecting the appropriate biological and physical
containment levels for each biological material handled. As discussed in ?Use of Chemical Materials,?
standard microbiological practices, such as limiting facility access, washing hands after handling,
decontaminating work surfaces, wearing gloves and other safety equipment, using biosafety cabinets, and
proper disposal, reduce risks resulting from exposure to biohazardous materials. Current state testing,
monitoring, and disposal regulations and EH&S programs pertaining to the management of
biohazardous materials, including infectious agents, would further ensure that the risks associated with
less than significant
the use of biohazardous substances remain .
Disposal of Hazardous Materials
Genentech disposes of hazardous wastes in compliance with Titles 8, 14, 17, and 22 of the California
less than significant
Code of Regulations, which ensures that impacts remain . Spent hazardous
materials generated on a daily basis in research, production, and maintenance facilities are placed in
special containers and are kept in ventilated accumulation areas out of normal use patterns. These
hazardous wastes are collected and accumulated in designated, secured areas designed to prevent
accidental release to the environment. Wastes are transported off site by licensed hazardous waste
transporters to permitted hazardous waste disposal facilities, and emergency response procedures for all
on-site storage sites are included in the Genentech Integrated Contingency Plan. Biohazardous wastes are
managed in the same way, though separately. Radioactive waste is collected, prepared, and packaged by
Genentech, then transported by a radioactive waste broker to a licensed radioactive waste disposal
facility.
Summary
While the proposed project would result in the development of additional laboratories and other research
facilities that would use, store, or require the transportation and disposal of hazardous materials, as well
as a limited increase in the average population that could be exposed to hazardous materials risks,
compliance with Genentech programs, practices, and procedures and safety standards related to the use,
disposal, and transport of hazardous materials and wastes, and the safety procedures mandated by
applicable federal, state, and local laws and regulations (RCRA, California Hazardous Waste Control Law,
and principles prescribed by the USDHS would ensure that risks resulting from the routine use of
less than significant
hazardous materials and disposal of hazardous wastes remain .
In addition, safety programs reduce the risk of exposure to biohazardous and chemical hazardous
materials by establishing protocols to safely handle and store hazardous substances, which ensures that a
less-than-significant impact would occur. Genentech ensures that their facilities are in compliance with
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the California Code of Regulations (Title 17) and conditions of the radioactive materials license, and the
utilization of radiation use authorizations and ongoing training regarding radiation safety also reduce the
risks from radiation-related use or disposal on-site, thereby ensuring that a less-than-significant impact
would occur. In addition, the CHP and USDOT strictly regulate hazardous materials transportation to
and from the site.
Although implementation of the proposed project would expose more people to potential hazards, safety
procedures mandated by federal and state laws and regulations, as previously described, as well as the
continuation of existing (or equivalent) Genentech programs, practices, and procedures would ensure
that the use, transport, or disposal of hazardous materials does not expose employees, visitors or the
nearby public to significant health or safety risks. As part of implementation of the proposed project,
federal and state law, as well as all Genentech procedures for handling hazardous wastes, would be
extended to all new facilities developed under the proposed project. The potential impact of increased
less
hazardous chemical, radioactive material, and biohazardous material use at Genentech would remain
than significant
. No mitigation is required.
Impact 4.6-2 Implementation of the proposed project would not expose construction
workers or Genentech employees to a significant hazard through the
renovation or demolition of buildings, or relocation of underground
less-than-
utilities, that contain hazardous materials. This is considered a
significant
impact.
Demolition of existing buildings could release hazardous materials if lead-based paint or asbestos-
containing materials are present in the structure(s). Any activity that involves cutting, grinding, or drilling
during building renovation or demolition, or relocation of underground utilities, could release friable
asbestos fibers and/or lead dust unless proper precautions are taken. As noted in Section 4.6.3 (Existing
Conditions), all applicable federal and state rules and regulations must be followed when asbestos-
containing materials are disturbed during construction or renovation. The notification of federal and
local government agencies is required prior to beginning any renovation or demolition that could disturb
asbestos, as well as the use of precautions and safe work practices to eliminate or reduce the potential for
release of asbestos fibers, and medical examinations and monitoring of employees engaged in activities
that could disturb asbestos. Similarly, there are programs directed at reducing lead exposure to a less-
than-significant level through education, inspection, testing, and removal. Genentech has a
comprehensive asbestos management program that includes regular surveys, annual notifications, and
signage in appropriate locations, as well as making information regarding the locations of asbestos on its
campus available to all employees through the company's intranet.
Buildings demolished during construction activities could also contain biohazardous materials, including
medical wastes. Genentech?s programs, practices, and procedures and current state testing, monitoring,
and disposal regulations pertaining to the management of biohazardous materials, including medical
waste, eliminate or reduce the potential for biohazardous substances to be present in fixtures or building
materials removed during demolition. In addition, the radioactive materials license requires testing and
implementation of decontamination and waste handling activities in accordance with applicable
regulations when facilities using radioactive materials are decommissioned for purposes of renovation or
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Chapter 4 Environmental Analysis
demolition. Compliance with federal and state health and safety laws and regulations, as well as following
existing (or equivalent) Genentech programs, practices, and procedures, would ensure that this impact
less than significant
remains. No mitigation is required.
Threshold Create a significant hazard to the public or the environment through reasonably
foreseeable upset and accident conditions involving the release of hazardous
materials into the environment.
Impact 4.6-3 Implementation of the proposed project would not create a significant
hazard to the public or the environment through reasonably foreseeable
upset and accident conditions involving the release of hazardous materials
less-than-significant
into the environment. This is considered a impact.
The precise increase in the amount of hazardous materials transported to or from the Genentech facility
as a result of implementation of the 2006 FMPU cannot be definitively predicted due to varying research
needs over time, which cannot be anticipated as part of this programmatic document, and changes in the
classification of hazardous materials. Nonetheless, the following discussion focuses on the potential
nature and magnitude of risks associated with the accidental release of hazardous materials typically used
on site.
Off-Site Transportation of Hazardous Materials
While Genentech programs, practices, and procedures specifically govern receipt of hazardous materials
at Genentech, the USDOT Office of Hazardous Materials Safety prescribes strict regulations for the safe
transportation of hazardous materials, as described in Title 49 of the Code of Federal Regulations, and
implemented by Title 13 of the California Code of Regulations. Transportation of hazardous materials
along any City or state roadways within or near Genentech is also subject to all hazardous materials
transportation regulations established by the California Highway Patrol pursuant to the California
Vehicle Code and the South San Francisco Fire Department (SSFFD).
The transportation of hazardous materials can result in accidental spills, leaks, toxic releases, fire, or
explosion. Licensed vendors bring hazardous materials to and from the Genentech facility, and manifests
are completed and maintained by Genentech for all hazardous waste that is transported in connection
with Genentech activities. The DTSC also maintains copies of Genentech?s waste manifests. In
conformance with legal requirements, incoming radioactive material is monitored and recorded for each
acquisition. Genentech's Shipping & Receiving Department processes and delivers all incoming
radioactive materials to users.
Hazardous waste shipments could occur as frequently as several times per week, barring unusual
circumstances, such as laboratory demolition. As previously mentioned, Section 31303 of the California
Code of Regulations requires that when hazardous materials are transported on state or interstate
highways, the highway(s) that offer the shortest overall transit time possible shall be used, and as required
by federal and state laws, all other all hazardous materials transportation regulations must be followed,
such as USDOT regulations for packaging and handling hazardous materials to prevent accidental spills
of hazardous materials during transit. Compliance with all applicable federal and state laws, as well as
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4.6 Hazards and Hazardous Materials
Genentech programs, practices, and procedures related to the transportation of hazardous materials will
less-
continue to reduce the likelihood and severity of accidents during transit, thereby ensuring that a
than-significant
impact would occur.
On-Site Transportation of Hazardous Materials
In addition to transport of hazardous materials to and from the Genentech facility, the movement of
hazardous materials also occurs among Genentech facilities (within buildings, from room to room,
within hallways, and up and down stairwells and elevators). Accidents could occur as these materials are
moved about the facility, and exposure of employees could occur through fire or explosion. Genentech's
various business units exercise appropriate practices to prevent against the risks of accidental spills or
releases of hazardous materials during internal transfers and movement of these materials. If a spill
occurs, the Genentech First Alert Team (FAT) would be immediately notified. If required, the area of
potential affect would be isolated and evacuated as appropriate in accordance with the Integrated
Contingency Plan to reduce the potential for human exposure and to allow for prompt and effective
cleanup by the Genentech FAT, an emergency response contractor, or the appropriate regulatory agency.
The consequences of spills as a result of a fall or dropping a container would depend on whether the
hazardous material was released, the specific hazards associated with the material, the facility design, and
the availability of emergency response equipment. In addition to health impacts associated with direct
contact from an accidental spill, indirect impacts could also occur. Spills that occur on permeable
surfaces may be difficult to decontaminate and may require complete removal of the surface. In areas
without adequate ventilation, including partially enclosed outdoor areas, such as walkways, stairwells, or
courtyards, vapors from released volatile materials could be trapped in stagnant air pockets, and persons
entering these areas after such a spill could be subject to health hazards associated with such vapors. In
these instances, all individuals would be evacuated from the affected area until the vapors dissipate to
safe levels as determined by the Genentech FAT.
To reduce the likelihood and severity of accidents during on-site transit, all applicable federal and state
laws and existing Genentech programs, practices, and procedures related to the transportation or cleanup
of hazardous materials (in the event of an accidental release) will continue to be implemented to ensure
less-than-significant
that a impact would occur. These laws, regulations, programs, practices, and
procedures include training regarding the handling of hazardous wastes and fully developed emergency
response programs. In summary, Genentech facility plans outline the procedures to follow in case of an
emergency involving hazardous materials.
Hazardous Materials Storage
Most hazardous materials stored on-site present little risk of upset. Hazardous materials are stored in
laboratories in designated secured areas designed to prevent accidental release to the environment.
Hazardous materials used for research are generally stored in laboratories in small, individual containers.
In the unlikely event of an accidental release, these small storage volumes limit potential consequences to
the individual laboratory in which they are stored. Compliance with all applicable federal and state laws
and existing Genentech programs, practices, and procedures related to the storage of hazardous materials
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will continue to be implemented to maximize containment (through safe handling and storage practices
described above) and to provide for prompt and effective clean-up if an accidental release occurs,
less-than-significant
thereby ensuring that a impact would occur.
Hazardous Materials Use
Hazardous materials use would present a slightly greater risk of accident than hazardous materials
storage. However, for those employees that work with hazardous materials, the amount of hazardous
materials that are handled at any one time is relatively small, reducing the potential consequences of an
accident during handling. Further, Genentech would continue to comply with federal and state laws and
existing Genentech programs, practices, and procedures to eliminate or reduce the consequence of
hazardous materials accidents. For example, staff who work around hazardous materials will continue to
wear appropriate protective equipment, and safety equipment is routinely available in all areas where
hazardous materials are used.
Major hazardous materials accidents are extremely infrequent, and additional emergency response
capabilities are not anticipated to be necessary to respond to the potential incremental increase in the
number of incidents that could result from implementation of the proposed project. Continued
compliance with all applicable federal, state, and local laws and regulations pertaining to the transport,
use, disposal, and handling of hazardous waste, as well as following Genentech programs, practices, and
less than significant
procedures, would ensure that this impact remains . No mitigation is required.
Impact 4.6-4 Implementation of the proposed project would not create a significant risk
of exposure of Genentech employees and construction workers to
contaminated soil or groundwater. Implementation of mitigation measure,
less than significant
MM 4.6-1 would ensure this impact remains .
While some Genentech facilities are included on lists and databases compiled by applicable federal, state,
and local agencies pursuant to Government Code Section 65962.5, these sites consist of registered active
or inactive USTs and hazardous materials storage locations, rather than contaminated sites (e.g., soil or
groundwater). All on-site USTs conform to applicable federal, state, and local regulations and are
registered and permitted by the SSFFD. In the event that USTs are uncovered or disturbed, they would
be closed in place or removed. While removal could pose health and safety risks, such as the exposure of
workers, tank handling personnel, and the public to tank contents or vapors, the potential risks, if any,
would be reduced by managing the tank according to established guidelines for investigation and closure
of USTs, as well as cleanup of sites contaminated by leaking USTs, to ensure that a less-than-significant
impact would occur.
Based on the historical industrial use of the area, it is possible that soil and/or groundwater contaminated
with petroleum hydrocarbons, metals, solvents, or other industrial materials could be encountered during
construction activities. Known historical contamination includes leaks from underground storage tanks,
which have been managed effectively in accordance with regulatory requirements. Low concentrations of
ammonia were discovered in soil and groundwater under a building on lower campus, for which the
Regional Water Quality Control Board issued a "No Further Action" letter in 2003. Naturally occurring
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4.6 Hazards and Hazardous Materials
asbestos in serpentine rock is known to be present in the middle campus area, and may be present in
other locations as well.
It is possible that contamination could exist in localized areas as the result of pesticide or herbicide use
during routine landscape/turf maintenance practices or in association with the removal or disturbance of
older underground utilities or unidentified buried debris. The use of pesticides is governed by the State
Department of Pesticide Regulation. With respect to other potential sources of soil contamination, such
as underground utilities or other unidentified buried debris, specific procedures would be followed in the
unlikely event that contaminated soil is discovered during construction activities to ensure that the risk of
exposure to Genentech employees or construction workers remains less than significant.
If required during construction activities, dewatering could result in the withdrawal of contaminated
groundwater. If the groundwater contains contaminants above regulatory levels, the water could present
a hazard to people or the environment unless properly managed. However, contractors would implement
best management practices during construction dewatering to avoid exposure of Genentech employees
or construction workers to potentially contaminated groundwater, such as groundwater testing,
containment of contaminated groundwater in storage tanks for subsequent treatment and/or disposal,
and/or the provision of release response information. In addition, subject to Section 13263 of the
California Water Code, the Regional Water Quality Control Board issues Waste Discharge Requirements
to control discharges (including groundwater) to land or water, and MM 4.6-1 would require that
Genentech follow specific procedures in the unlikely event that contaminated groundwater is discovered
during construction activities to ensure that the risk of exposure to Genentech employees or
construction workers remains less than significant.
The following mitigation measure shall be implemented throughout the proposed project planning
horizon:
MM 4.6-1 While not expected to occur on-site, if contaminated soil and/or groundwater is encountered
during the removal of on-site debris or during excavation and/or grading activities, the
construction contractor(s) shall stop work and immediately inform the appropriate Genentech
representative. An on-site assessment shall be conducted to determine if the discovered materials
pose a significant risk to the public or construction workers. If the materials are determined to
pose such a risk, a remediation plan shall be prepared and submitted to comply with applicable
legal requirements to assure the proper handling and management of contaminated soil and/or
debris, and the protection of human health and the environment for the new building. Soil
remediation methods could include, but are not necessarily limited to, excavation and on-site
treatment, excavation and off-site treatment or disposal, and/or treatment without excavation.
Remediation alternatives for cleanup of contaminated groundwater could include, but are not
necessarily limited to, on-site treatment, extraction and off-site treatment, and/or disposal. The
construction schedule shall be modified or delayed to ensure that construction will not inhibit
remediation activities and will not expose the public or construction workers to significant risks
associated with hazardous conditions.
less than significant
Following MM 4.6-1 would ensure that this impact remains by providing specific
procedures to follow in the event that contaminated soil and/or groundwater is discovered.
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Threshold Emit hazardous emissions or handle hazardous or acutely hazardous materials,
substances, or waste within one-quarter mile of an existing or proposed school.
Impact 4.6-5 The proposed project would not emit hazardous emissions or handle
hazardous or acutely hazardous materials, substances, or waste within one-
no impact
quarter mile of an existing or proposed school. There would be .
There are no existing schools within one-quarter mile of the MEIR Study Area. There are existing and
planned child centers within the MEIR Study Area, but no schools. The MEIR Study Area is located in
an area zoned for industrial uses only. Thus, no school can be proposed within one-quarter mile of the
no impact
MEIR Study Area. There would be . No mitigation is required.
Threshold Be located on a site which is included on a list of hazardous materials sites compiled
pursuant to Government Code Section 65962.5 and, as a result, would it create a
significant hazard to the public or the environment.
Impact 4.6-6 Implementation of the proposed project would not result in construction of
facilities on a site containing hazardous materials, and thus would not
create a significant hazard to the public or environment. Following
less than significant
MM 4.6-1 would ensure that this impact remains .
The EDR Report identifies the locations of known hazardous materials sites on-site based upon a review
of federal, state, and county hazardous waste lists and databases pursuant to Government Code
Section 65962.5. The lists and databases include, but are not limited to, the Department of Toxic
Substances Control Hazardous Waste and Substances Site List (Cortese List), the Resource Conservation and
Recovery Act (RCRA) database, and the California Hazardous Material Incident Report System (CHMIRS).
These lists and databases contain information about asbestos waste, underground storage tanks,
photoprocessing chemicals, PCBs, unspecified solvent and organic mixture wastes, unspecified aqueous
solution, metal sludge, other hazardous materials monitored by statute or regulation, known releases of
hazardous substances, and locations where radioactive or other hazardous materials are stored or used.
There are no listed contaminated soil or groundwater sites on-site; however, there are on-site active or
inactive USTs included on the lists and databases, as well as locations where hazardous materials are
stored and/or used. These USTs conform to applicable federal, state, and local regulations and are
registered and permitted by the SSFFD. If future UST-related cleanup were determined to be necessary,
all work would be performed in accordance with appropriate guidelines of the regional Underground
Storage Tank Program. All non-UST hazardous waste storage locations are managed in accordance with
all applicable federal and state laws, such as RCRA and the California Hazardous Waste Control Law, as
well as with all existing Genentech programs, practices, and procedures described in Section 4.6.3
(Existing Conditions) and Section 4.6.4 (Regulatory Framework). Following MM 4.6-1 would ensure that
less than significant
this impact remains . No mitigation is required.
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Threshold For a project located within an airport land use plan or, where such a plan has not
been adopted, within two miles of a public airport or public use airport, would the
project result in a safety hazard for people residing or working in the project area.
Impact 4.6-7 The proposed project is located within an airport land use plan; however,
the proposed project would not result in a safety hazard for people residing
no impact
or working in the project area. There would be .
The MEIR Study Area is located within two miles of the SFIA. Both the existing and the proposed
Genentech R&D Overlay District areas are within the San Francisco International Airport Flight Zone
and are subject to the Federal Aviation Administration (FAA) Airport Height Limits established in the
San Mateo County Airport Land Use Plan. In addition to FAA standards, the 2006 FMPU keeps a
maximum building height limitation of 150 feet above ground level on buildings within the MEIR Study
no impact
Area, which is in compliance with the FAA standards. There would be . No mitigation is
required.
Threshold For a project within the vicinity of a private airstrip, would the project result in a safety
hazard for people residing or working in the project area.
Impact 4.6-8 The proposed project is not located in the vicinity of a private airstrip.
no impact
There would be .
no impact
No private airstrips are located in the vicinity of the MEIR Study Area. There would be . No
mitigation is required.
Threshold Impair implementation of or physical interference with an adopted emergency
response plan or emergency evacuation plan.
Impact 4.6-9 Implementation of the proposed project would not impair implementation
of, or physically interfere with, an adopted emergency response or
emergency evacuation plan. Implementation of mitigation measures MM
less than
4.6-2(a) and 4.6-2(b) would ensure this impact remains
significant
.
Construction and operation activities associated with development under the proposed project could
potentially affect emergency response or evacuation plans due to temporary construction barricades or
other obstructions that could impede emergency access on-site. However, through implementation of
MM 4.6-2(a), multiple emergency access or evacuation routes would be provided on-site to ensure that in
the event one roadway or travel lane is temporarily blocked, another may be utilized. Furthermore,
ongoing coordination between Genentech and local agencies pursuant to MM 4.6-2(b) would ensure that
roadway or travel lane closures will be coordinated with emergency response personnel to ensure that
individual development projects under the 2006 FMPU would not impair implementation of, or
physically interfere with, emergency response and evacuation efforts.
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The following mitigation measures shall be implemented throughout the 2006 FMPU planning horizon:
MM 4.6-2(a) To the extent feasible, the project applicant shall maintain at least one unobstructed lane in both
directions on the site?s roadways. At any time only a single lane is available, Genentech shall
provide a temporary traffic signal, signal carriers (i.e., flagpersons), or other appropriate traffic
controls to allow travel in both directions. If construction activities require the complete closure of
a roadway segment, Genentech shall provide appropriate signage indicating alternative routes.
MM 4.6-2(b) To ensure adequate access for emergency vehicles when construction projects would result in
temporary lane or roadway closures, the project applicant shall consult with the South San
Francisco Police and Fire Departments to disclose temporary lane or roadway closures and
alternative travel routes.
Following MM 4.6-2(a) and MM 4.6-2(b) ensures that impacts associated with emergency response or
less than significant
evacuation would remain by providing multiple emergency access or evacuation
routes and coordinating roadway or travel lane closures with emergency response personnel.
Threshold Expose people or structures to a significant risk of loss, injury or death involving wild
land fires, including where wild lands are adjacent to urbanized areas or where
residences are intermixed with wild lands.
Impact 4.6-10 The proposed project would not expose people or structures to a
significant risk of loss, injury or death involving wild land fires. There
no impact
would be .
The MEIR Study Area is highly developed, and no wildlands are intermixed within this urbanized area.
The MEIR Study Area is bordered by developed land to the north, east, and south. To the west is the
San Francisco Bay. No wildlands are directly adjacent to the MEIR Study Area. The closest wildlands
no
area, San Bruno Mountain County Park, is located approximately one mile away. There would be
impact
. No mitigation is required.
4.6.4References
Dyett & Bhatia, 2005. Draft Genentech Central Campus Ten-Year EIR Study, November.
Environmental Data Resources. Inc. 2006. EDR Historical Topographic Map Report, Years 1913 through 1993,
March 22.
???. 2006. The EDR Aerial Photo Decade Package, Years 1946 through 1998, March 22.
???. 2006. The EDR?City Directory Abstract, Years 1990 through 2005, March 23.
???. 2006. The EDR Radius Map with GeoCheck, March 22.
Genentech. n.d. Core Plan: Emergency Response Procedures at Genentech?s South San Francisco Site.
???. 2004. Genentech?s Corporate Environmental Performance Report.
http://www.gene.com/gene/about/environmental/pdf/environ-report.pdf, Accessed March 2006.
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4.6 Hazards and Hazardous Materials
???. 2006. Website: http://www.gene.com. Accessed March 2006.
Harnish, Jim. 2005. Written communication from Mintier & Associates to EIP Associates, Memorandum
dated December 22.
Marshall, Keith. 2006. E-mail communication between City of South San Francisco Fire Department and
EIP Associates, March 3.
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